While topical treatments and cosmetic ‘tweakments’ can smooth skin and knock a few years off your appearance, they’re only one piece of the glow-up puzzle – true regeneration starts from within. A powerful amino acid with regenerative properties, Lysine is known to support the body’s own collagen production, immune resilience and overnight repair. Providing the building blocks for collagen synthesis, Lysine helps to create the essential protein's triple-helix structure and cross-linking collagen fibres for strength and stability deep within the dermis.

We know that Lysine is essential to any holistic wellness routine. Upgrading our biologist-developed blend of 28 Vitamins, Minerals, Amino Acids, Adaptogens and Omega 3s, we’ve recently enhanced our Morning & Night supplement with Lysine for added skin, immunity and menopause support.

One of nine essential amino acids, Lysine is not naturally produced in the body and must be obtained through diet or supplementation. Found in protein-rich foods like lean meats, eggs, legumes and dairy, Lysine plays a fundamental role in collagen synthesis, calcium absorption and the production of enzymes and hormones.

But Lysine's role extends beyond its metabolic functions – in recent years, dermatologists have explored its potential as a functional compound in skin health. According to the American Academy of Dermatology, collagen stores are depleted by as much as 30% in the first five years following menopause onset, making Lysine a critical tool in replenishing lost collagen post-menopause. 

Found in our Night dose, the Lysine in our Morning & Night supplement gets to work while you sleep – aligning with the restorative repair phase of your circadian rhythm to noticeably improve how you look and feel.

If you were to head to Instagram now and thumb through your feed, you’d likely be flooded with collagen supplement ads and cosmetic injectors speaking about how to encourage collagen production with Botox and filler.

It’s no secret that the key to youthful, resilient skin lies in collagen – a vital protein that provides structure, elasticity and hydration to the dermis, the middle layer of skin. As the most abundant protein in the human body, collagen makes up about one third of all protein in our tissues, from skin and nails to hair and bone. As we age, collagen is slowly depleted – leading to sagging skin, brittle nails, dull hair and weak bones.

The good news? Lysine supplementation can facilitate the production of collagen, acting as a binding agent that secures collagen fibres and promotes skin regeneration. A 2022 review published in the Journal of Dermatological Science highlighted Lysine’s role in dermal repair, noting that a Lysine deficiency can lead to delayed wound healing and loss of skin integrity. What’s more, Lysine supports skin hydration and maintains the skin barrier, making it a key ally in combating dryness, fine lines loss of elasticity.

With 92% of participants noting better skin in our independent, placebo-controlled clinical trial, Morning & Night visibly improves skin on a cellular level, partnering Lysine with other skin-supporting ingredients like Glycine and Vitamin C.

If you’re sniffling as you read this, you’re not alone – the stresses of modern life can lead to a weakened immune system, making you more susceptible to colds, flus and other infections. Aside from practicing proper hand hygiene and maintaining a good diet, exercise regimen and sleep routine, supplements can give you the extra boost needed to keep illness at bay.

Lysine plays a critical role in immune strength and resilience – by serving as a critical substrate for the synthesis of antibodies and various immune mediators, Lysine supplementation enhances the body’s capacity to mount a defence against pathogens. Lysine also contributes to the modulation of inflammatory responses, promoting a balanced immune reaction that mitigates excessive tissue damage while effectively clearing infection.

Our award-winning Morning & Night supplement, rich in immune-boosting ingredients like Lysine,  Vitamin C and Zinc, is proven to boost immunity on a cellular level. In our independent clinical trial, 84% noticed a stronger immune system with the support of Morning & Night.

As former first lady and outspoken menopause awareness advocate, Michelle Obama, will tell you, menopause is a period during which the body undergoes a profound hormonal shift – oestrogen levels drop, metabolism slows, and muscle mass, skin elasticity and bone density begins to decline. Lysine, though not a hormone regulator in the classical sense, supports processes that counteract these effects.

One of Lysine’s lesser-known benefits is its role in calcium absorption and bone integrity. In a 2021 study published in Nutrients, researchers found that Lysine supplementation helped to increase calcium retention in postmenopausal women, potentially reducing the risk of osteoporosis.

Lysine also aids in the synthesis of carnitine, a compound that converts fatty acids into energy and supports lean muscle mass. For women experiencing menopausal fatigue or muscle loss, Lysine supplementation may offer subtle yet valuable support in maintaining strength and stamina.

Morning & Night was developed with aging – and menopause – in mind. Packed with 28 carefully calibrated ingredients to balance hormones and support your menopause journey, Morning & Night can ease difficult menopause symptoms and help you to enjoy the new season of life – Morning & Night subscriber, Emma, says, “Morning & Night has helped me immensely through the menopause. I now sleep soundly most nights, waking early to feel energised and ready to start the day… I’m a huge fan and I tell all my friends.”